[A role of insomnia in the development of silent cerebral infarctions].
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(9. Vyp. 2):3-7
Authors: Tikhomirova OV, Kozhevnikova VV, Zybina NN, Startseva ON, Bobko OV
Abstract
AIM: To investigate the relationship between insomnia, hemostatic abnormalities and silent cerebral infarctions.
MATERIAL AND METHODS: A complex study of 76 male patients, aged 40-85, with vascular risk factors was carried out. Magnetic resonance imaging (MRI) data was used to verify presence of silent cerebral infarctions; the presence and severity of insomnia were determined using questionnaires and polysomnography. Laboratory diagnosis included a complete assessment of hemostatic system with thrombodynamics test.
RESULTS: Patients were divided into 2 groups according the MRI data. The 1st group included 20 men with less than 4 silent cerebral infarctions, the 2nd group 56 men with multiple silent cerebral infarctions – from 5 to 25. Chronic insomnia was diagnosed in 35 (46%) of patients, more frequently in the second group (25% and 54% respectively, p