Effective CPAP therapy is associated with improved cardiovascular and pulmonary-related morbidity and mortality. Nonadherence to CPAP leads to worsened health outcomes, but it is unclear whether this translates into increased 30-day hospital readmissions. A recent study published in the Journal of Clinical Sleep Medicine (JCSM) showed that Nonadherence to CPAP is associated with increased 30-day all-cause and cardiovascular-cause readmission in patients with OSA. Thirty-day all-cause and cardiovascular-cause readmission rate was significantly higher in the nonadherent group, with an adjusted odds ratio (OR) of 3.52 and 2.31 respectively. This study suggests that ensuring CPAP adherence is crucial in addressing general and cardiovascular-related healthcare utilization and morbidity in patients with OSA.